ABSTRACT : The delivery system for relief materials including food essentials and medical requirements and shelter needs to affected people depends heavily on Humanitarian supply chain management (HSCM) during disaster response operations. Humanitarian logistics operation faces major difficulties which stem from the unpredictability of needs and defective infrastructure and depleted resources. People with industrial engineering knowledge use optimization methods alongside data analysis techniques and resource management models to create innovative improvements for emergency supply chains. The research utilizes potential applications of industrial engineering methods for improving disaster response operation frameworks. It also assesses supply chain performance improvement through quantitative modeling along with case study analysis and survey research and optimization algorithms and predictive analytics along with automated logistics systems. The study gives humanitarian organizations understanding of how implementing industrial engineering approaches will enhance coordination while decreasing delays and maximizing resource use. The study serves to expand humanitarian logistics literature through its development of an organized method to optimize disaster relief operations