ABSTRACT : The increase in supply chain efficiency through Lean manufacturing depends on three key factors: waste reduction along with better inventory control and supplier teamwork enhancement. The research evaluates how supply chain performance is influenced by lean principles namely Just-In- Time (JIT), Six Sigma and Total Quality Management (TQM). The research study incorporates three methods which include surveys with supply chain executives and case studies of major manufacturers along with statistical computations to measure direct benefits from lean implementation. Organizations that implement lean principles achieve major production improvements together with supply chain resilience while reducing costs. The analysis shows that companies face important barriers which include demanding cultural change and the necessary integration of advanced technologies. The study enhances existing knowledge by supplying experimental evidence about lean manufacturing’s ability to promote sustainable supply chain operations.