ABSTRACT: We analyze the determinants of the “Human Resources” in European countries during the period2010-2019. The variable “Human resources” is considered as a proxy for human capital. We use a dataset fromEuropean Innovation Scoreboard that analyze 36 countries. Data are processed using panel with fixed andrandom effects, pooled OLS, WLS and dynamic panel.Theliterature relative to human capital and humanresources is analyzed considering that the usage of Artificial Intelligence and automation can transform theworkforce into a “useless class”. Results show that the variable “Human Resources” is positively associatedwith the sequent macro-variables “Attractive Research Systems”, “Education”, “Innovation Index”, “Linkages”,“Performance and Structure of the Economy” and negatively associated with “Finance and Support”,“Governance and Policy Framework”, “Innovators”, “Intellectual Assets” and “Sales Impact”.